Gareth King Colloquial English Audio
Тори Дагеч, Елена Владимировна Исакова. ISBN:, ; Audio CD, 162 Pages, approx. 4 hours/track. Gareth King.. eBook. Â« Two audiocassette tapes;.
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80 Comments w/c 8/03/15 16:51 View Cart Most. English, Written and Spoken. Download Colloquial English Audio books on Audible.comÂ .Prenatal diagnosis of aortic valve stenosis. Is echocardiography predictive?
Aortic valve stenosis affects 2 to 3 in every 1000 live births. Maternal echocardiography is the only prenatal diagnostic test available for this condition and should be performed by an experienced examiner at least twice in pregnancy to minimize false positive and negative findings. The value of other available prenatal tests is uncertain. We assessed the diagnostic accuracy of maternal echocardiography and fetal aortic biometry to predict aortic valve stenosis by postnatal echocardiography. This was a retrospective review of 27 cases of aortic valve stenosis diagnosed by postnatal echocardiography. Prenatal echocardiography was available in 20 cases and aortic valve biometry was available in 26. The sensitivity and specificity of maternal echocardiography were 78% and 80%, respectively; that of fetal aortic biometry was 88% and 85%. The positive predictive value of maternal echocardiography was 64% and that of fetal aortic biometry was 81%. The negative predictive value of maternal echocardiography was 95% and that of fetal aortic biometry was 94%. Prenatal diagnosis of aortic valve stenosis by maternal and fetal echocardiography is not necessarily accurate and fetal aortic biometry alone should not be used in the prenatal assessment of aortic valve stenosis.Neuregulin 1 in patient with a complex and recurrent chromosomal translocation.
The gene for neuregulin 1 (NRG1) is localized on the 17p11.2-p12 chromosome region and encodes a 60 kDa growth factor that mediates growth and differentiation of various cell types including the Schwann cells. NRG1 is expressed in the developing neural tube and may play a role in neuronal migration and survival. Herein, we report the case of a patient with mental retardation with a complex and recurrent chromosomal translocation in which two abnormal NRG1 genes were detected. Genetic analysis revealed an inverted t(1;17)(p34;q11.2) with the extra cen17hter segment being in cis to a translocated region of the chromosome 17p11