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Biography

Li Fangkuo, sometimes transliterated Li Fàngkuo ( born December 21, 1912 – died September 14, 2012) is a Chinese geneticist who made important contributions to modern research into genetic disorders. He was jointly awarded the 1978 Nobel Prize in Physiology or Medicine with the American bacteriologist James D. Watson and the American molecular biologist Sydney Brenner for discovering “the double-helix structure of DNA.” Fangkuo was the first Chinese scientist to receive a Nobel Prize. He was born in the city of Jinjiang, Guangdong Province (now known as Shenzhen), into a poor family, the grandson of Fang Zhiyun, a mathematician.

Fangkuo’s family was in the silk-making business, and as a boy he grew up with silkworms. During his student days, he wrote in his spare time a story called A Thousand Years of Solitude. With the encouragement of Xu Zhimo, Fangkuo entered a medical school in China in 1934. After graduation, in 1937, he obtained the position of a tutor at the School of Basic Medicine of Sun Yat-sen University. Fangkuo was fascinated by medical problems, particularly those related to genetics.

1939 saw the outbreak of the Second Sino-Japanese War; at the time, he was assigned to an army unit. He became seriously ill, and medical attention was inadequate. Fangkuo felt he had no choice but to try an operation, after which he developed an ulcer. After World War II, Fangkuo saw the opportunity to study genetics. In 1947 he went to the National Institute of Genetics in Tokyo, Japan, where he and his Chinese colleague, Yan Baijing, discovered the purple bacterial enzyme DNA polymerase, which they used to recreate the structure of DNA.

In the early 1950s, Fangkuo returned to China, where he became the research leader of

https://colab.research.google.com/drive/1XYhVoi98N0ciSduYGlvXjJEii0tA0CMl
https://colab.research.google.com/drive/1t9H9Qr9CZYrvt5sddSe6JLZRoxXolGhj
https://colab.research.google.com/drive/1MLk-KqaANLW6HF_87IjnlOg4WQMPWqvt
https://colab.research.google.com/drive/1chvYviQRInR00CSAkTgcuuVwcGMy6fzT
https://colab.research.google.com/drive/1Qaw2fZj0M62dndSWYB0_Jwe5ik5DA8Ta

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